Anticholinergic and Spasm-Relieving Drugs The anticholinergic class of medicines includes darifenacin , dicyclomine , flavoxate , hyoscyamine , methantheline , oxybutynin , solifenacin , tolterodine , fesoterodine , and trospium . Anticholinergic agents can help relieve urge incontinence. Anticholinergic means to oppose or counteract the experience of specific nerve fibers that cause the bladder to contract cialis 20 mg . Some tricyclic antidepressants , such as imipramine , nortriptyline , or amitriptyline , have solid anticholinergic effects and could be prescribed to treat incontinence.

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Antifibrinolytics inhibit glycine receptor activity in the mind and cause seizures Antifibrinolytic drugs are accustomed to prevent loss of blood during surgery frequently, but sometimes cause convulsive seizures. In this presssing issue of the Journal of Clinical Investigation, researchers led by Beverly Orser at the University of Toronto investigated the molecular mechanisms that underlie this side effect. By studying antifibrinolytics in mice, Orser and co-workers found that the drugs inhibited the activity of glycine receptors in the brain, leading to seizures. Seizures could possibly be prevented by co-treatment with the overall anesthetic isoflurane.