Antibody-drug conjugates : an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals By April Cashin-Garbutt Interview conducted, BA Hons What are antibody-medication conjugates and what are they used for? ADCs are used for a new type of targeted therapy that consists of a specific anti-tumor antibody or antibody fragment associated with a potent anti-cancer therapeutic ed medications . Our ADCs deliver deactivated cytotoxins specifically to a tumor cell. Once in the tumor cell, the cytotoxins are released from the ADC, regaining their complete cytotoxic activity, leading to rapid cell loss of life. What exactly are the aims of using ADCs? Desire to for this class of therapy can be to mix better tumour eliminating properties with lower side effects for cancer patients.

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‘This research demonstrates that reducing the time to analysis and ideal treatment through use of a rapid and accurate pathogen identification system, like the MALDI Biotyper, when integrated into a thorough antibiotic stewardship program, improves patient care while significantly reducing amount of stay and total costs.’ The authors from The Methodist Medical center in Houston Texas set out to assess how patient care could be improved and cost benefits achieved by a combination of speedy pathogen identification and a systematic method of antimicrobial stewardship. Study patients with gram-negative blood attacks were assigned to either routine care and attention or even to the intervention program, which included speedy pathogen identification and instant antimicrobial susceptibility tests using the MALDI Biotyper, along with protocols for timely communication of leads to inform therapeutic decisions.